Starting in our 30s, we lose volume in our face-under our eyes, in our cheeks and around our mouths. Later on, in our 40s and 50s, our skin and muscles start to stretch from loss of collagen and elastin. To stimulate collagen production, tighten loose skin and add volume back to the face there are a myriad of surgery-free options to choose from, including dermal fillers, thread lifts, lasers and platelet-rich plasma (PRP) therapy. Similar to PRP, platelet-rich fibrin (PRF) is a new, all-natural solution that can treat common areas that show the first signs of aging, like under-eye hollows and deflated cheeks.

While the use of PRP and PRF is growing in popularity as a viable option for cosmetic treatment, it has not yet been approved by the FDA. “Hopefully these treatments do what they’re purported to do, but at this time there is no published scientific data that back up those claims,” says La Jolla, CA plastic surgeon Robert Singer, MD. However, as the demand grows for more organic rejuvenation treatments, more and more patients are turning to therapies that harness the growth factors in our blood for cosmetic enhancement.

We talked to Los Angeles facial plastic surgeon Kian Karimi, MD, who showed off the results of a PRF treatment on an episode of The Doctors to understand more about the treatment that is being referred to as a “natural” filler

Dr. Pontius: While traditional fillers like hyaluronic acid products provide volume by filling the treated area, EZGEL PRF promotes your body’s own healing processes. It works to restore volume and improve skin quality by stimulating collagen production and enhancing skin texture naturally. Unlike fillers, which are synthetic, PRF uses your own cells, making it a more holistic approach to facial rejuvenation.

 

Dr. Pontius: EZGEL PRF offers several benefits, including:

  • Natural results: Since it uses your own blood components, the results are subtle and natural-looking.
  • Long-lasting effects: The regenerative properties of PRF help to stimulate collagen over time, making the results last longer than many traditional fillers.
  • Safe and biocompatible: Because the material comes from your own body, there’s little to no risk of allergic reactions or complications.
  • Versatility: EZGEL PRF can treat fine lines, wrinkles, acne scars, and under-eye hollows, among other areas.

 

Dr. Pontius: EZGEL PRF is ideal for patients looking for natural facial rejuvenation without synthetic fillers. It’s perfect for those wanting to improve skin texture, address fine lines, or add subtle volume in areas like the under-eyes or cheeks. Patients with signs of aging or those who prefer a more natural approach to facial aesthetics are excellent candidates. However, a consultation is necessary to determine if PRF is the right treatment for you.

 

Dr. Pontius: The EZGEL PRF treatment is quick and minimally invasive. First, we draw a small amount of your blood and process it to extract the PRF. The gel is then injected into the areas of concern, such as the under-eye hollows, cheeks, or other regions showing signs of aging. We recommend a series of three treatments spaced 4-6 weeks apart for optimal results. Each session takes about 45 minutes to an hour, and most patients experience minimal downtime afterward.

 

Dr. Pontius: Patients typically start noticing improvements in their skin within a few weeks as the PRF stimulates collagen production. The results continue to improve over the next several months, with the full effect visible after 3-6 months. The longevity of the results varies depending on individual factors but generally lasts 12-18 months. After completing the recommended 3 treatments, many patients enjoy long-lasting rejuvenation.

 

Dr. Pontius: One of the great benefits of EZGEL PRF is that there’s minimal downtime. Patients may experience some mild swelling or bruising at the injection sites, but this typically subsides within a few days. Most patients can return to their normal activities immediately after the procedure.